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AimsTo investigate the temporal pattern of appearance of a new psychoactive

substance (4-fluoroamphetamine) on the Dutch drug market,

as well as its patterns of use and effects.

DesignData from the Drug Information and Monitoring System (DIMS) was used

to investigate the emergence of 4-fluoroamphetamine on the Dutch drug market.


An online questionnaire was used to study its patterns of use and effects.

SettingDutch drug-related websites and social media.

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ParticipantsA convenience sample of 249 lifetime 4-fluoroamphetamine users was

recruited through the internet.Measurements ,

Samples containing 4-fluoroamphetamine .

were extracted from the DIMS database for further

investigation. Patterns of use,

settings of use and the subjective effects of 4-fluoroamphetamine,

amphetamine and 3,4-methylenedioxymethamphetamine (MDMA) ,

were investigated with the online questionnaire.

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Findings4-Fluoroamphetamine was first encountered on the Dutch drug market,

mainly sold as amphetamine or ecstasy ,

between 2007-2009. These misrepresented drug samples declined.

when the MDMA and amphetamine markets recovered after a period of shortage.

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whereas purposefully bought 4-fluoroamphetamine samples showed an increase.

Survey results showed that 4-fluoroamphetamine

is predominantly used for its specific effects,

rather than its legal status

The subjective effects of 4-fluoroamphetamine

were compared with those of amphetamine and MDMA.

Subjective effect scores of 4-fluoroamphetamine ,ranged between those of amphetamine and MDMA.

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Conclusions The stimulant 4-fluoroamphetamine is increasingly popular

in the Netherlands, which might be due to its subjective effects profile,

which lies intermediate between amphetamine and MDMA.

The phenethylamine 4-fluoroamphetamine (4-FA) is a so-called novel psychoactive.

substance with a chemical structure resembling that of amphetamine and MDMA.

Since 4-FA users report their subjective experience ranges between the effects

induced by amphetamine and MDMA,

and it is known that both substances can produce an altered state of consciousness,

this study tests whether 4-FA induces a psychedelic state.


Additional information

20GM, 50GM, 100GM, 250GM

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