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and how does it work (mechanism of action)?
Firstly, Lisinopril is an angiotensin converting enzyme (ACE) inhibitor used for treating high blood pressure,
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heart failure and for preventing kidney failure due to high blood pressure and diabetes.
Hence, Other ACE inhibitors include:
ACE is important because it is an enzyme responsible for producing the chemical, angiotensin II.
Above all, Angiotensin II causes muscles in most arteries,
including the arteries of the heart,
to contract, thereby narrowing the arteries and elevating blood pressure.
After that, ACE inhibitors such as lisinopril lower blood pressure by reducing the production of angiotensin II,
thereby relaxing arterial muscle and enlarging arteries.
When the blood pressure is lower,
the heart – including the failing heart – does not have to work as hard to pump blood.
The arteries supplying the heart with blood also enlarge during treatment with ACE inhibitors.
This increases the flow of blood and oxygen to the heart,
further improving the ability of the heart to pump blood.
During, The effects of ACE inhibitors are particularly beneficial to people with congestive heart failure.
In the kidneys, the narrowing of the arteries by angiotensin II decreases blood flow and damages the kidneys.
ACE inhibitors enlarge and reduce the blood pressure in the arteries going to the kidney.
This reduces damage to the kidneys caused by the high blood pressure.
The FDA approved lisinopril in December 1987.
What brand names are available for lisinopril?
Zestril, Prinivil, and Qbrelis are the brand names available for this drug.
Is lisinopril available as a generic drug? Yes, it’s available in generic form.